BioSig Technologies, Inc. (BSGM) provided an update for investors via a Shareholder Letter posted on the company’s website this morning. The letter highlights some of the recent positive developments for the company, including the collaboration with Mayo Clinic and the recent $5.0 million financing. I am optimistic about the future of BioSig and PURE EP™, a novel surface electrocardiogram (EKG) and intracardiac multichannel recording and analysis system.

Collaboration With Mayo

On March 23, 2017, BioSig announced it has signed a ten-year strategic agreement with a team of Mayo Clinic physicians. This new, expanded collaboration builds upon the work realized under the Advanced Clinical Research Program signed with Mayo Clinic in March 2016. BioSig intends to work closely with Mayo electrophysiologists, Drs. Samuel Asirvatham and K. L. Venkatachalam, to develop advanced clinical features and applications for its PURE EP System, as well as to leverage the company’s core competency in physiologic signal processing to develop future technologies.

Mayo is expected to contribute know-how, intellectual property and clinical support to the partnership. The company expects joint patent filings to come out of the relationship. It’s an exciting transaction for BioSig to partner with one of the nation’s leading centers for cardiology. It’s also a huge validation of the platform and opportunity to develop next-generation devices. Mayo has a proven track record of success in developing cutting-edge technologies and innovative treatment methods. Mayo’s R&D budget exceeds $650 million, putting it on par with several leading medical device players. I believe this relationship provides validation and credibility to PURE EP.

Expanding Opportunities

PURE EP stands for Precise Uninterrupted Real-time evaluation of Electrograms (PURE) EP Systems. BioSig’s proprietary system is similar to traditional EP recording systems produced by GE Healthcare or St. Jude Medical, which have two computer screens and allow for independent, real-time review capabilities. However, where PURE EP is superior is in the systems very low noise, coupled with a minimum gain and maximum bandwidth. PURE EP also delivers unique proprietary topology features, including high input impedance, high common mode rejection ratio, and rejection of noise generated by an RF ablation generator.